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Practice Guideline - Kidney Disease - Early Detection and Treatment

The United States has 19 million people with chronic kidney disease. Poor outcomes such as kidney failure, cardiovascular disease and premature death can be prevented or delayed. The National Kidney Foundation recommends that all people at increased risk for kidney disease be tested for markers of kidney damage. MCI endorses the following recommendations:

  1. Risk factors for kidney disease include:
    Diabetes Autoimmune diseases
    Hypertension Age > 65*
    Urinary Tract Infections Ethnic minority status*
    Drug Exposure (NSAID, etc) Positive Family History*
    Urinary Stones *not a Medicare billable diagnosis
  2. Evaluate patients at risk for kidney disease yearly for albuminuria.  Testing can be done with a spot urine, using albumin specific dipsticks.
  3. Confirm a positive dipstick test (Microalbumin/Creatinine > 30 or  Micral >20) with a quantitative measurement by sending a spot urine to MCL.

  4. Evaluate patients with confirmed kidney disease to determine:

    • Diagnosis (diabetes, vascular, glomerular, interstitial, cystic)
    • Co-morbid conditions (cardiovascular, anemia, etc.)
    • Severity by assessing GFR (normal is greater than 90)
      • GFR = (140-age) x weight in Kilograms X 0.85 in females
        72 x serum creatinine in mg/dl
  5. Treatment of chronic kidney disease includes:

    • Control of blood pressure to less than 130/85
    • Use of ACEI or ARB medications
    • Control of lipids to LDL < 100
    • Avoidance of excessive protein intake (1.2 gm / Kg / day)
    • Cessation of tobacco use
    • Referral for progression of disease

References: 

  1. “Nondiabetic kidney disease” NEJM, Nov. 7, 2002
  2. “National Kidney Foundation Chronic Kidney Disease Guideline” on line at:  http://www.kidney.org/professionals/doqi/kdoqi/toc.htm  

Variation from this guideline is always acceptable if  in the opinion of the attending physician individual circumstances require it.